Action Of 777 Ointment On Psoriasis

Psoriasis is an Autoimmune disorder of skin, resulting in hyper proliferating outer layer of the skin.

In normal condition Epithelial turnover takes place in about 25 days and division of single keratinocytes occur once in 60 days.

In Psoriasis state the Epithelialization occurs in about 36 hours and so the division of keratinocytes, which reduces to 10 days.

The phenomenon collectively leads to hyperkeratinized state.

At time inflamatory process does occur in order to permeate more inflow of blood, to the site.

Then there will be silvery scales on redish colour lesions.

There Are Many Types of Psoriasis

Guttate Psoriasis

This is usually seen in children, and Adolescents. This may be the first sign of Psoriasis. The rash often appears rapidly and individual lesions are droplet shaped, small and scaly.

Bouts of Guttate Psoriasis usually clear in a few months. But patients may develop the plaque pattern later.

Erythrodermic Psoriasis

The skin becomes universally red and scaly. Shivering compensates for the considerable heat loss. This unpleasant variant may be initiated by the irritant effect of tar or Dithranol or the withdrawal of systemic or potent topical corticosteroids.

Postular Psoriasis

The generalised form is a rare but serious type of Psoriasis. The onset is sudden, with myriads of small sterile pustules errupting on an erythematous base.

The patient is ill with a swinging pyrexia, coinciding with the appearance of new pustules, and requires hospital admission.

The localised form is more common. It most often involves the palms and soles. The erruption consists of numerous small sterile pustules lying on an erythematous base, which leave brown macules or scaling in their wake. Some regard this as a separate disease entity.

Rupioid Psoriasis

Rupioid Psoriasis describes a grossly huperkeratotic form of chronic plaque Psoriasis.

There are thick scales on the lesions. Lesions are somewhat big in size.

Scalp Psoriasis

This occurs particularly in children and young people. This may be associated with thick white lumps of scale adhering to the scalp and hair shaft.

Subungual Hyperkeratosis

In this condition, there may be nail changes, such as hperkeratinized, thick, weakened nails.

Salmon Patch & Pitting Psoriasis

In this condition, nail changes occur such as manifestation of pittings on nail, onycholysis, yellow-brown areas of discoloration which is called Salmon patches.

Psoriatic Arthritis

This is a seronegative inflammatory Arthritis found in patients with Psoriasis, a past of family history of Psoriasis or with characteristic changes in nail.